MEBMB

Articles

• CLARE Tony
  17 August 2016

  Research Topics
  marine chemical ecology with a special interest in marine invertebrate larval settlement, especially barnacles

• Discrimination of four marine biofilm-forming bacteria by LC-MS metabolomics and influence of culture parameters
  31 March 2017

  Most marine bacteria can form biofilms, and they are the main components of biofilms observed on marine surfaces. Biofilms constitute a widespread life strategy, as growing in such structures offers many important biological benefits. The molecular compounds expressed in biofilms and, more generally, the metabolomes of marine bacteria remain poorly studied. In this context, a nontargeted LC–MS metabolomics approach of marine biofilm-forming bacterial strains was developed. Four marine bacteria, Persicivirga (Nonlabens) mediterranea TC4 and TC7, Pseudoalteromonas lipolytica TC8, and Shewanella sp. TC11, were used as model organisms. The main objective was to search for some strain-specific bacterial metabolites and to determine how culture parameters (culture medium, growth phase, and mode of culture) may affect the cellular metabolism of each strain and thus the global interstrain metabolic discrimination. LC–MS profiling and statistical partial least-squares discriminant analyses showed that the four strains could be differentiated at the species level whatever the medium, the growth phase, or the mode of culture (planktonic vs biofilm). A MS/MS molecular network was subsequently built and allowed the identification of putative bacterial biomarkers. TC8 was discriminated by a series of ornithine lipids, while the P. mediterranea strains produced hydroxylated ornithine and glycine lipids. Among the P. mediterranea strains, TC7 extracts were distinguished by the occurrence of diamine derivatives, such as putrescine amides.

• Discrimination de vins rosés par métabolomique non-ciblée
  25 April 2019
• Metabolomic profiling reveals deep chemical divergence between two morphotypes of the zoanthid Parazoanthus axinellae
  2 June 2016
• A versatile electrochemical sensing receptor based on a molecularly imprinted polymer
  2 June 2016
• Caractérisation et activité anti-biofilm des exopolysaccharides de la bactérie marine Pseudoalteromonas ulvae TC14
  15 September 2016
• Cinétique de colonisation et variabilité spatiotemporelle des diatomées dans les biofilms marins côtiers
  25 August 2023, by JFB
• Symbiontes photosynthétiques de Petrosia ficiformis (Spongiaires) : Caractérisation et production de métabolites actifs en antifouling
  9 June 2016, by Hugues BRISSET

  Beginning: 2008
  Defence: June 6, 2012

• LC-MS based metabolic profiling of marine bacterial strains demonstrates variation between free-living and biofilm lifestyles
  12 July 2016
• La métabolomique en région SUD PACA : principaux acteurs et secteurs d’activité
  13 June 2019