ORTALO-MAGNE Annick

Articles

• Towards new polymer materials for the regulation of quorum sensing as a biofilm control strategy
  14 January, by CaB
• Impact of hydrodynamics on community structure and metabolic production of marine biofouling formed in a highly energetic estuary
  25 March 2024, by JFB
• Caractérisation par analyse métabolomique de biomarqueurs bactériens au sein de biofilms marins
  6 June 2016
• Etude par métabolomique de l’impact du cuivre sur des souches bactériennes issues d’une zone côtière polluée: La rade de Toulon
  3 June 2016
• Discrimination of four marine biofilm-forming bacteria by LC-MS metabolomics and influence of culture parameters
  31 March 2017

  Most marine bacteria can form biofilms, and they are the main components of biofilms observed on marine surfaces. Biofilms constitute a widespread life strategy, as growing in such structures offers many important biological benefits. The molecular compounds expressed in biofilms and, more generally, the metabolomes of marine bacteria remain poorly studied. In this context, a nontargeted LC–MS metabolomics approach of marine biofilm-forming bacterial strains was developed. Four marine bacteria, Persicivirga (Nonlabens) mediterranea TC4 and TC7, Pseudoalteromonas lipolytica TC8, and Shewanella sp. TC11, were used as model organisms. The main objective was to search for some strain-specific bacterial metabolites and to determine how culture parameters (culture medium, growth phase, and mode of culture) may affect the cellular metabolism of each strain and thus the global interstrain metabolic discrimination. LC–MS profiling and statistical partial least-squares discriminant analyses showed that the four strains could be differentiated at the species level whatever the medium, the growth phase, or the mode of culture (planktonic vs biofilm). A MS/MS molecular network was subsequently built and allowed the identification of putative bacterial biomarkers. TC8 was discriminated by a series of ornithine lipids, while the P. mediterranea strains produced hydroxylated ornithine and glycine lipids. Among the P. mediterranea strains, TC7 extracts were distinguished by the occurrence of diamine derivatives, such as putrescine amides.

• Characterization of the metabolic production of marine biofilms. Towards an application to the study of complex biofilms in situ
  29 November 2018

  Beginning: November 2018

• Metabolomic and proteomic changes induced by growth inhibitory concentrations of copper in the biofilm-forming marine bacterium Pseudoalteromonas lipolytica
  23 September 2019
• Design of molecularly imprinted polymers with anti-quorum sensing properties
  6 January 2025, by CaB
• Disrupting quorum sensing alters social interactions in Chromobacterium violaceum
  16 July 2021, by JFB
• Shear stress controls prokaryotic and eukaryotic biofilm communities together with EPS and metabolomic expression in a semi‑controlled coastal environment in the NW Mediterranean Sea
  20 December 2024, by JFB