CULIOLI Gérald

Articles

• Kinetics of multi-species biofilms on artificial surfaces in static and dynamic mode using a multi-omics approach
  4 September 2018
• Linear diterpenes from the marine brown alga Bifurcaria bifurcata: A chemical perspective
  3 June 2016
• Effet de l’hydrodynamisme sur la production biochimique de biofilms marins
  25 August 2023, by JFB
• Interactions between macro-algae and associated bacteria: biofilm control by surface secondary metabolites in the Mediterranean brown seaweed Taonia atomaria
  8 June 2016
• Discrimination of four marine biofilm-forming bacteria by LC-MS metabolomics and influence of culture parameters
  31 March 2017

  Most marine bacteria can form biofilms, and they are the main components of biofilms observed on marine surfaces. Biofilms constitute a widespread life strategy, as growing in such structures offers many important biological benefits. The molecular compounds expressed in biofilms and, more generally, the metabolomes of marine bacteria remain poorly studied. In this context, a nontargeted LC–MS metabolomics approach of marine biofilm-forming bacterial strains was developed. Four marine bacteria, Persicivirga (Nonlabens) mediterranea TC4 and TC7, Pseudoalteromonas lipolytica TC8, and Shewanella sp. TC11, were used as model organisms. The main objective was to search for some strain-specific bacterial metabolites and to determine how culture parameters (culture medium, growth phase, and mode of culture) may affect the cellular metabolism of each strain and thus the global interstrain metabolic discrimination. LC–MS profiling and statistical partial least-squares discriminant analyses showed that the four strains could be differentiated at the species level whatever the medium, the growth phase, or the mode of culture (planktonic vs biofilm). A MS/MS molecular network was subsequently built and allowed the identification of putative bacterial biomarkers. TC8 was discriminated by a series of ornithine lipids, while the P. mediterranea strains produced hydroxylated ornithine and glycine lipids. Among the P. mediterranea strains, TC7 extracts were distinguished by the occurrence of diamine derivatives, such as putrescine amides.

• L’analyse du métabolome : un outil pour la compréhension des interactions écologiques entre organismes marins ?
  8 June 2016
• French Mediterranean and Atlantic populations of the brown algal genus Taonia (Dictyotales) display differences in phylogeny, surface metabolomes and epibacterial communities
  24 August 2021, by JFB
• Anti-microfouling properties of compounds isolated from several Mediterranean Dictyota spp.
  2 June 2016
• Metabolomic and proteomic changes induced by growth inhibitory concentrations of copper in the biofilm-forming marine bacterium Pseudoalteromonas lipolytica
  23 September 2019
• LC/ESI-MSn and 1H HR-MAS NMR analytical methods as useful taxonomical tools within the genus Cystoseira C. Agardh (Fucales; Phaeophyceae)
  3 June 2016