CULIOLI Gérald

Articles

• Utilisation de l’approche des réseaux moléculaires pour l’annotation de nouvelles classes de glycérolipides au sein du métabolome de la macroalgue brune Taonia atomaria
  13 June 2019
• Polymère à empreinte moléculaire: synthèse, caractérisation et utilisation dans le domaine des capteurs
  8 June 2016
• Impact of Aqueous Extract Artemisia Herba-Alba Leaves as a Green Inhibitor against Acid Activation of 2024 Aluminum Alloy
  16 April 2025, by IM
• Exploring the role of macroalgal surface metabolites on the settlement of the benthic dinoflagellate {Ostreopsis} cf. {ovata}
  26 July 2020
• Impact of hydrodynamics on community structure and metabolic production of marine biofouling formed in a highly energetic estuary
  25 March 2024, by JFB
• Caractérisation par analyse métabolomique de biomarqueurs bactériens au sein de biofilms marins
  6 June 2016
• Etude par métabolomique de l’impact du cuivre sur des souches bactériennes issues d’une zone côtière polluée: La rade de Toulon
  3 June 2016
• Performance assessment of marine paint formulations acting through the release of antifouling agents: Evaluation of leaching and ecotoxicity
  6 June 2016
• Discrimination of four marine biofilm-forming bacteria by LC-MS metabolomics and influence of culture parameters
  31 March 2017

  Most marine bacteria can form biofilms, and they are the main components of biofilms observed on marine surfaces. Biofilms constitute a widespread life strategy, as growing in such structures offers many important biological benefits. The molecular compounds expressed in biofilms and, more generally, the metabolomes of marine bacteria remain poorly studied. In this context, a nontargeted LC–MS metabolomics approach of marine biofilm-forming bacterial strains was developed. Four marine bacteria, Persicivirga (Nonlabens) mediterranea TC4 and TC7, Pseudoalteromonas lipolytica TC8, and Shewanella sp. TC11, were used as model organisms. The main objective was to search for some strain-specific bacterial metabolites and to determine how culture parameters (culture medium, growth phase, and mode of culture) may affect the cellular metabolism of each strain and thus the global interstrain metabolic discrimination. LC–MS profiling and statistical partial least-squares discriminant analyses showed that the four strains could be differentiated at the species level whatever the medium, the growth phase, or the mode of culture (planktonic vs biofilm). A MS/MS molecular network was subsequently built and allowed the identification of putative bacterial biomarkers. TC8 was discriminated by a series of ornithine lipids, while the P. mediterranea strains produced hydroxylated ornithine and glycine lipids. Among the P. mediterranea strains, TC7 extracts were distinguished by the occurrence of diamine derivatives, such as putrescine amides.

• Characterization of the metabolic production of marine biofilms. Towards an application to the study of complex biofilms in situ
  29 November 2018

  Beginning: November 2018